A ceramic/metal laminated system has lately been proposed by the authors. It is capable of maintaining high mechanical strength and structural integrity after high-temperature thermal shock. In this investigation, a multilayered, multimaterial system with strong interface, subjected to thermal shock loading, was analyzed. The analysis was based on a 1-D finite difference scheme and considers the thermal residual stresses. Using a failure criterion based on crack initiation, the number of broken layers due to thermal shock and the residual mechanical strength at room temperature was determined. A comparison with experimental results of three different lay-ups was made, demonstrating the ability of the program to predict the experimental results. The program was thus shown to be a significant tool for designing multimaterial multilayered systems for thermal shock applications.