Analgesic effect of ceruletide compared with pentazocine in biliary and renal colic: A prospective, controlled, double-blind study

M. Lishner, R. Lang, I. Jutrin, C. De-Paolis, M. Ravid

Research output: Contribution to journalArticlepeer-review

Abstract

The analgesic effect of ceruletide in biliary and renal colic was evaluated by a randomized, double-blind study in 82 patients. Ceruletide was compared with pentazocine, a well-established analgetic agent. Rapid and effective analgesia was obtained by intramuscular injection of ceruletide 0.5 μg/kg in 56 patients with biliary colic. The analgesic effect of ceruletide compared well with pentazocine 0.5 mg/kg im, and was associated with remarkably fewer side effects. In 26 patients with renal colic, ceruletide was significantly inferior to pentazocine. These data support the recommendation of ceruletide as a first-choice analgetic agent for biliary colic.

Original languageEnglish
Pages (from-to)433-436
Number of pages4
JournalDrug Intelligence and Clinical Pharmacy
Volume19
Issue number6
DOIs
StatePublished - 1985

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