Anaerobic glycolysisThe metabolism of the preovulatory human oocyte

Ilan Gull, Eli Geva*, Liat Lerner-Geva, Joseph B. Lessing, Igal Wolman, Ami Amit

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

Objectives: The aim of the study was to investigate the process of glycolysis in gonadotropic, hyperstimulated, human ovarian follicles. Study design: Follicular fluid (FF) lactate and glucose concentrations were measured in 26 patients with tubal factor infertility undergoing in vitro fertilization treatment. Results: The mean FF lactate and glucose concentrations were 3.17±0.90 mM with positive, and 3.39±0.91 mM with negative correlations to follicular size. FF lactate concentration correlated negatively to glucose levels. Conclusions: Our study confirms in vivo the anaerobic glycolysis in gonadotropic, hyperstimulated human ovarian follicles. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume85
Issue number2
DOIs
StatePublished - Aug 1999

Keywords

  • Follicular fluid
  • Glucose
  • Glycolysis
  • Lactate
  • Metabolism
  • Oocytes

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