Recent advances in the understanding of the molecular virulence mechanisms of Shigella have helped to develop a new generation of candidate Shigella vaccines. Approaches that are currently under active study include construction of hybrid Shigella-E. coli strains, performance of attenuating mutations in vitro on natural Shigella strains and acellular, lipopolysaccharide-based vaccines.
|Number of pages||3|
|Journal||Israel Journal of Medical Sciences|
|State||Published - 1994|
- Infectious disease
- Molecular biology