An update on Shigella vaccines

S. Ashkenazi*, D. Cohen

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Recent advances in the understanding of the molecular virulence mechanisms of Shigella have helped to develop a new generation of candidate Shigella vaccines. Approaches that are currently under active study include construction of hybrid Shigella-E. coli strains, performance of attenuating mutations in vitro on natural Shigella strains and acellular, lipopolysaccharide-based vaccines.

Original languageEnglish
Pages (from-to)495-497
Number of pages3
JournalIsrael Journal of Medical Sciences
Issue number5-6
StatePublished - 1994
Externally publishedYes


  • Infectious disease
  • Lipopolysaccharide
  • Molecular biology
  • Shigella
  • Vaccines


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