Abstract
Recent advances in the understanding of the molecular virulence mechanisms of Shigella have helped to develop a new generation of candidate Shigella vaccines. Approaches that are currently under active study include construction of hybrid Shigella-E. coli strains, performance of attenuating mutations in vitro on natural Shigella strains and acellular, lipopolysaccharide-based vaccines.
| Original language | English |
|---|---|
| Pages (from-to) | 495-497 |
| Number of pages | 3 |
| Journal | Israel Journal of Medical Sciences |
| Volume | 30 |
| Issue number | 5-6 |
| State | Published - 1994 |
| Externally published | Yes |
Keywords
- Infectious disease
- Lipopolysaccharide
- Molecular biology
- Shigella
- Vaccines