Darier-White disease is a relatively common autosomal dominant genodermatosis caused by mutation in the ATP2A2 gene. It is characterized by multiple warty papules coalescing into plaques in the seborrheic areas and by specific histological skin changes. Palm and sole involvement in Darier-White disease is usually mild, mainly featuring discrete and small keratotic papules. We present a unique case of Darier-White disease presenting with a diffuse, mutilat-ing hystrix-like palmoplantar keratoderma.
|Number of pages||3|
|Journal||Acta Dermatovenerologica Croatica|
|State||Published - 17 Mar 2021|
- Darier-White disease
- palmoplantar keratoderma