An open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndrome

Avi Leader; Daniella Amital; Alan Rubinow; Howard Amital

doi:10.1111/j.1749-6632.2009.04811.x

An open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndrome

Avi Leader, Daniella Amital, Alan Rubinow, Howard Amital^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

12 Scopus citations

Abstract

Fibromyalgia is an ill-defined condition that causes pain and disability but still lacks effective treatment. The aim of this open-label study was to assess the efficacy of administering a food supplement, creatine monohydrate, in an "add on" to existing therapies in patients with fibromyalgia. This study included 30 patients with fibromyalgia. After 8 weeks of receiving creatine, we witnessed a significant improvement in parameters reflecting severity of fibromyalgia, quality of life and sleep, disability, and pain. These results deteriorated 4 weeks after stopping creatine therapy. The findings of this study are preliminary and limited due to the small sample and relatively high rate of dropouts.

Original language	English
Title of host publication	Contemporary Challenges in Autoimmunity
Publisher	Blackwell Publishing Inc.
Pages	829-836
Number of pages	8
Volume	1173
ISBN (Print)	9781573317627
DOIs	https://doi.org/10.1111/j.1749-6632.2009.04811.x
State	Published - Sep 2009

Keywords

Anxiety
Depression
Fibromyalgia
Pain
Quality of life

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10.1111/j.1749-6632.2009.04811.x

Cite this

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An open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndrome. / Leader, Avi ; Amital, Daniella; Rubinow, Alan et al.
Contemporary Challenges in Autoimmunity. Vol. 1173 Blackwell Publishing Inc., 2009. p. 829-836.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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An open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndrome

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