@article{f41a23fb4ce747cf8ba9d5599bb7a977,
title = "An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets",
abstract = "Zhang et al. construct a transcriptional network for IL-27-mediated Il10 production in CD4 T cells, characterize the function of 16 Il10 regulators, and uncover the role of two transcription factors, Prdm1 and Maf, in driving Il10 production in all T helper cells and in maintaining immune homeostasis in the colon.",
keywords = "IL-10, IL-27, Maf, Prdm1, T helper cells, Tr1, Treg, colitis, transcriptional network",
author = "Huiyuan Zhang and Asaf Madi and Nir Yosef and Norio Chihara and Amit Awasthi and Caroline Pot and Conner Lambden and Amitabh Srivastava and Burkett, {Patrick R.} and Jackson Nyman and Elena Christian and Yasaman Etminan and Annika Lee and Helene Stroh and Junrong Xia and Katarzyna Karwacz and Thakore, {Pratiksha I.} and Nandini Acharya and Alexandra Schnell and Chao Wang and Lionel Apetoh and Orit Rozenblatt-Rosen and Anderson, {Ana C.} and Aviv Regev and Kuchroo, {Vijay K.}",
note = "Publisher Copyright: {\textcopyright} 2020 The Authors",
year = "2020",
month = nov,
day = "24",
doi = "10.1016/j.celrep.2020.108433",
language = "אנגלית",
volume = "33",
journal = "Cell Reports",
issn = "2639-1856",
publisher = "Cell Press",
number = "8",
}