Abstract
Using in vivo translational gene fusion in Escherichia coli K-12 we identified a gene that is specifically induced by heavy metals, cadmium, mercury and zinc, at nmolar concentrations. This gene was identified by homology to known zinc and cadmium transporters. We created a disruption of the gene that resulted only in a minor increase in sensitivity to cadmium, suggesting that the fusion, which is at the carboxy-terminal end of the molecule, probably allows for at least partial activity of the protein. Copyright (C) 1998 Federation of European Microbiological Societies.
Original language | English |
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Pages (from-to) | 107-111 |
Number of pages | 5 |
Journal | FEMS Microbiology Letters |
Volume | 167 |
Issue number | 2 |
DOIs | |
State | Published - 15 Oct 1998 |
Keywords
- Cadmium
- Gene regulation
- Heavy metal
- Mercury
- Stress response
- Zinc