TY - JOUR
T1 - An equivalent Markov Model for Gillespie's Stochastic Simulation Algorithm for biochemical systems
AU - Bustin, Ronit
AU - Messer, Hagit
PY - 2006
Y1 - 2006
N2 - Mathematical/statistical modeling of biological systems is a desired goal for many years. It aims to be able to accurately predict the operation of such systems under various scenarios using computer simulations. In this paper we revisit Gillespie' Stochastic Simulation Algorithm for biochemical systems and we suggest an equivalent Markov Model for it. We show that under certain conditions it is a 1 st order homogenous Markov process and we analyze these conditions. Our suggested model can be used to simulate the probability density function of a biochemical processes which, in turn, can be used for applying statistical signal processing and information theory tools on them.
AB - Mathematical/statistical modeling of biological systems is a desired goal for many years. It aims to be able to accurately predict the operation of such systems under various scenarios using computer simulations. In this paper we revisit Gillespie' Stochastic Simulation Algorithm for biochemical systems and we suggest an equivalent Markov Model for it. We show that under certain conditions it is a 1 st order homogenous Markov process and we analyze these conditions. Our suggested model can be used to simulate the probability density function of a biochemical processes which, in turn, can be used for applying statistical signal processing and information theory tools on them.
UR - http://www.scopus.com/inward/record.url?scp=84862634358&partnerID=8YFLogxK
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AN - SCOPUS:84862634358
SN - 2219-5491
JO - European Signal Processing Conference
JF - European Signal Processing Conference
T2 - 14th European Signal Processing Conference, EUSIPCO 2006
Y2 - 4 September 2006 through 8 September 2006
ER -