TY - JOUR
T1 - Amniotic fluid components and changes due to storage conditions
AU - Zaidman, J. L.
AU - Waron, M.
AU - Meyer, S.
AU - Micle, S.
PY - 1992
Y1 - 1992
N2 - The composition of amniotic fluid was found to vary in dependence on storage conditions. Catalytic concentrations of creatine kinase and lactate dehydrogenase were considerably decreased after storage at -20°C, and the decreases were less marked after storage at -70°C. Other analytes were more stable. Consequently, the optimal storage conditions for amniotic fluid samples may differ for various analytes. The low inter-individual variability of some analytes (Na, K, Ca, Cl) suggests that their concentrations are homeostatically controlled during the gestational period studied. In contrast, the high variability of enzyme activities may be due to more rapid quantitative changes during normal gestation; in addition, enzyme activities may be affected by certain pathological and non-pathological conditions of the fetus.
AB - The composition of amniotic fluid was found to vary in dependence on storage conditions. Catalytic concentrations of creatine kinase and lactate dehydrogenase were considerably decreased after storage at -20°C, and the decreases were less marked after storage at -70°C. Other analytes were more stable. Consequently, the optimal storage conditions for amniotic fluid samples may differ for various analytes. The low inter-individual variability of some analytes (Na, K, Ca, Cl) suggests that their concentrations are homeostatically controlled during the gestational period studied. In contrast, the high variability of enzyme activities may be due to more rapid quantitative changes during normal gestation; in addition, enzyme activities may be affected by certain pathological and non-pathological conditions of the fetus.
UR - http://www.scopus.com/inward/record.url?scp=0026602213&partnerID=8YFLogxK
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AN - SCOPUS:0026602213
SN - 0939-4974
VL - 30
SP - 43
EP - 45
JO - European Journal of Clinical Chemistry and Clinical Biochemistry
JF - European Journal of Clinical Chemistry and Clinical Biochemistry
IS - 1
ER -