Altered heart rate variability in panic disorder patients

Ehud Klein; Elena Cnaani; Tamar Harel; Simon Braun; Shlomo A. Ben-Haim

doi:10.1016/0006-3223(94)00130-U

Altered heart rate variability in panic disorder patients

Ehud Klein^*, Elena Cnaani, Tamar Harel, Simon Braun, Shlomo A. Ben-Haim

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

Resting electrocardiographic recordings were obtained from 10 patients with panic disorder (PD) and 14 normal controls. Signal analysis of the beat-to-beat heart rate variability was performed by means of power spectrum analysis. The analysis revealed that patients with PD had marked reduction in the high-frequency peaks of the power spectrum densities. An Energy Ratio Index (ERI), which accurately differentiated between patients and controls, was calculated. In PD patients, a significant correlation was demonstrated between the clinical ratings and the energy ratios. Our findings suggest that decreased heart rate variability may be a characteristic of PD. The importance of this finding as a diagnostic marker and the underlying pathophysiological mechanisms need to be further explored.

Original language	English
Pages (from-to)	18-24
Number of pages	7
Journal	Biological Psychiatry
Volume	37
Issue number	1
DOIs	https://doi.org/10.1016/0006-3223(94)00130-U
State	Published - 1 Jan 1995
Externally published	Yes

Keywords

Panic disorder
heart rate variability
power spectrum
signal analysis

Access to Document

10.1016/0006-3223(94)00130-U

Cite this

@article{f17f029733d545d19fe3f3925dfad25c,

title = "Altered heart rate variability in panic disorder patients",

abstract = "Resting electrocardiographic recordings were obtained from 10 patients with panic disorder (PD) and 14 normal controls. Signal analysis of the beat-to-beat heart rate variability was performed by means of power spectrum analysis. The analysis revealed that patients with PD had marked reduction in the high-frequency peaks of the power spectrum densities. An Energy Ratio Index (ERI), which accurately differentiated between patients and controls, was calculated. In PD patients, a significant correlation was demonstrated between the clinical ratings and the energy ratios. Our findings suggest that decreased heart rate variability may be a characteristic of PD. The importance of this finding as a diagnostic marker and the underlying pathophysiological mechanisms need to be further explored.",

keywords = "Panic disorder, heart rate variability, power spectrum, signal analysis",

author = "Ehud Klein and Elena Cnaani and Tamar Harel and Simon Braun and Ben-Haim, {Shlomo A.}",

year = "1995",

month = jan,

day = "1",

doi = "10.1016/0006-3223(94)00130-U",

language = "אנגלית",

volume = "37",

pages = "18--24",

journal = "Biological Psychiatry",

issn = "0006-3223",

publisher = "Elsevier USA",

number = "1",

}

TY - JOUR

T1 - Altered heart rate variability in panic disorder patients

AU - Klein, Ehud

AU - Cnaani, Elena

AU - Harel, Tamar

AU - Braun, Simon

AU - Ben-Haim, Shlomo A.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Resting electrocardiographic recordings were obtained from 10 patients with panic disorder (PD) and 14 normal controls. Signal analysis of the beat-to-beat heart rate variability was performed by means of power spectrum analysis. The analysis revealed that patients with PD had marked reduction in the high-frequency peaks of the power spectrum densities. An Energy Ratio Index (ERI), which accurately differentiated between patients and controls, was calculated. In PD patients, a significant correlation was demonstrated between the clinical ratings and the energy ratios. Our findings suggest that decreased heart rate variability may be a characteristic of PD. The importance of this finding as a diagnostic marker and the underlying pathophysiological mechanisms need to be further explored.

AB - Resting electrocardiographic recordings were obtained from 10 patients with panic disorder (PD) and 14 normal controls. Signal analysis of the beat-to-beat heart rate variability was performed by means of power spectrum analysis. The analysis revealed that patients with PD had marked reduction in the high-frequency peaks of the power spectrum densities. An Energy Ratio Index (ERI), which accurately differentiated between patients and controls, was calculated. In PD patients, a significant correlation was demonstrated between the clinical ratings and the energy ratios. Our findings suggest that decreased heart rate variability may be a characteristic of PD. The importance of this finding as a diagnostic marker and the underlying pathophysiological mechanisms need to be further explored.

KW - Panic disorder

KW - heart rate variability

KW - power spectrum

KW - signal analysis

UR - http://www.scopus.com/inward/record.url?scp=0028796794&partnerID=8YFLogxK

U2 - 10.1016/0006-3223(94)00130-U

DO - 10.1016/0006-3223(94)00130-U

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0028796794

SN - 0006-3223

VL - 37

SP - 18

EP - 24

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 1

ER -

Altered heart rate variability in panic disorder patients

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this