TY - JOUR
T1 - Alterations in QT dispersion in the surface electrocardiogram of female adolescents diagnosed with restricting-type anorexia nervosa
AU - Nahshoni, Eitan
AU - Weizman, Abraham
AU - Yaroslavsky, Amit
AU - Toledano, Anat
AU - Sulkes, Jacqueline
AU - Stein, Daniel
PY - 2007/4
Y1 - 2007/4
N2 - Objective: QT dispersion (QTd), defined as the difference between the longest interval and the shortest interval in the 12-lead electrocardiogram (ECG), is a measure of myocardial repolarization inhomogeneity. We assessed QTd in malnourished anorexia nervosa (AN) inpatients and following weight restoration. Methods: QTd analysis, anthropometric evaluations, and laboratory tests were carried out in 30 malnourished female adolescent AN restricting-type (AN-R) inpatients and following weight restoration. Results: A significant increase was found in weight/height ratio and body mass index from malnourished stage to weight restoration, paralleled by a significant decrease in QTd (70±16 vs. 47±16 ms; P<.0001). No correlations were found between ECG indices and anthropometric and laboratory measures. Conclusion: Elevated QTd in malnourished AN-R inpatients may indicate possible cardiac autonomic imbalance and/or myocardial damage, likely corrected following weight restoration.
AB - Objective: QT dispersion (QTd), defined as the difference between the longest interval and the shortest interval in the 12-lead electrocardiogram (ECG), is a measure of myocardial repolarization inhomogeneity. We assessed QTd in malnourished anorexia nervosa (AN) inpatients and following weight restoration. Methods: QTd analysis, anthropometric evaluations, and laboratory tests were carried out in 30 malnourished female adolescent AN restricting-type (AN-R) inpatients and following weight restoration. Results: A significant increase was found in weight/height ratio and body mass index from malnourished stage to weight restoration, paralleled by a significant decrease in QTd (70±16 vs. 47±16 ms; P<.0001). No correlations were found between ECG indices and anthropometric and laboratory measures. Conclusion: Elevated QTd in malnourished AN-R inpatients may indicate possible cardiac autonomic imbalance and/or myocardial damage, likely corrected following weight restoration.
KW - Anorexia nervosa
KW - Autonomic nervous system
KW - Eating disorders
KW - Electrocardiogram
KW - QT dispersion
UR - http://www.scopus.com/inward/record.url?scp=33947316136&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychores.2006.10.023
DO - 10.1016/j.jpsychores.2006.10.023
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AN - SCOPUS:33947316136
SN - 0022-3999
VL - 62
SP - 469
EP - 472
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
IS - 4
ER -
