Alteration of platelet benzodiazepine receptors by stress of war

Ronit Weizman, Nathaniel Laor, Leon Karp, Efrat Dagan, Ahuva Reiss, Dalit E. Dar, Leo Wolmer, Moshe Gavish*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Mitochondrial benzodiazepine receptors play a major role in steroidogenesis. The authors determined plasma cortisol levels, platelet levels of mitochondrial benzodiazepine receptors, and anxiety and depression scores in 11 civilians exposed to the Persian Gulf war. The density of mitochondrial benzodiazepine receptors was 22% and 15% lower before and during the war, respectively, than 4 weeks after the end of the war. Relief of stress led to an increase in receptors, which correlated with the improvement in anxiety but not mood.

Original languageEnglish
Pages (from-to)766-767
Number of pages2
JournalAmerican Journal of Psychiatry
Volume151
Issue number5
DOIs
StatePublished - May 1994

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