AIDS in the pre-AIDS era.

D. Huminer*, J. B. Rosenfeld, S. D. Pitlik

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


A search of the medical literature published since 1950 disclosed 19 cases of probable AIDS reported before the start of the current epidemic. These cases retrospectively met the Centers for Disease Control's surveillance definition of the syndrome and had a clinical course suggestive of AIDS. The reports originated from North America, Western Europe, Africa, and the Middle East. The mean age of patients was 37 years, and the ratio of male to female patients was 1.7:1. Sixteen patients had opportunistic infections(s) without Kaposi's sarcoma. The remainder had disseminated Kaposi's sarcoma. The commonest opportunistic infection was Pneumocystis carinii pneumonia. Two patients were reported to be homosexual. Three others had been living in Africa, and one patient was born in Haiti. In two instances concurrent or subsequent opportunistic infection occurred in family members. All patients died 1 month to 6 years after the initial manifestation of disease. In view of the historical data, unrecognized cases of AIDS appear to have occurred sporadically in the pre-AIDS era.

Original languageEnglish
Pages (from-to)1102-1108
Number of pages7
JournalReviews of Infectious Diseases
Issue number6
StatePublished - 1987
Externally publishedYes


Dive into the research topics of 'AIDS in the pre-AIDS era.'. Together they form a unique fingerprint.

Cite this