TY - JOUR
T1 - Aging of wound healing in an experimental model in mice
AU - Hiss, J.
AU - Hirshberg, A.
AU - Dayan, D. F.
AU - Bubis, J. J.
AU - Wolman, M.
PY - 1988
Y1 - 1988
N2 - Healing of incised wounds in the backs of mice was studied to establish criteria that would allow the timing of stages during cutaneous wound healing. Starting from day 4 after the incisions were made, three mice were killed every 3 days until day 40. Sections from wounds were stained with hematoxylin-eosin, a reticulin procedure, and picrosirius red. Unstained sections were used for blue autofluorescence. The significance of the findings from the ultraviolet study was limited, but the picrosirius red-polarized light procedure was found to be useful for estimating the age of the repair process as polarization colors of greater wavelengths progressively increased with the age of the lesion.
AB - Healing of incised wounds in the backs of mice was studied to establish criteria that would allow the timing of stages during cutaneous wound healing. Starting from day 4 after the incisions were made, three mice were killed every 3 days until day 40. Sections from wounds were stained with hematoxylin-eosin, a reticulin procedure, and picrosirius red. Unstained sections were used for blue autofluorescence. The significance of the findings from the ultraviolet study was limited, but the picrosirius red-polarized light procedure was found to be useful for estimating the age of the repair process as polarization colors of greater wavelengths progressively increased with the age of the lesion.
UR - http://www.scopus.com/inward/record.url?scp=0024202971&partnerID=8YFLogxK
U2 - 10.1097/00000433-198812000-00008
DO - 10.1097/00000433-198812000-00008
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AN - SCOPUS:0024202971
SN - 0195-7910
VL - 9
SP - 310
EP - 312
JO - American Journal of Forensic Medicine and Pathology
JF - American Journal of Forensic Medicine and Pathology
IS - 4
ER -