Age and pregnancy rates in in vitro fertilization

Dov Dicker, Jack A. Goldman*, Jacob Ashkenazi, Dov Feldberg, Michal Shelef, Talia Levy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

The influence of women[s age on the results of in vitro fertilization (IVF) was analyzed in 1801 women undergoing the procedure. Advancing age was found to be related to significant reduced success rates from an average of 30.1% per transfer below the age of 36 years to 15.9% per transfer at 37 years or more (P<0.001). The decrease was related to a reduction in oocyte production (five at 25 years or less, four below the age of 40 years, three at 40 years or more, and two in the 43 to 47-year group) and probably-due to reduced implantation. It is concluded that a woman's age must be considered an important prognostic factor when IVF is suggested.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalJournal of in Vitro Fertilization and Embryo Transfer
Volume8
Issue number3
DOIs
StatePublished - Jun 1991

Keywords

  • age
  • elderly woman
  • in vitro fertilization
  • oocytes
  • pregnancy rates

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