Age and indication for referral to capsule endoscopy significantly affect small bowel transit times: The given database

Zvi Fireman*, Yael Kopelman, Shosh Friedman, Hagit Ephrath, Eran Choman, Hila Debby, Rami Eliakim

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study was to examine the effect of age and selected indications for capsule endoscopy on small bowel transit times. Data on 67 clinical studies (790 subjects with different gastrointestinal pathologies [49.5% males; mean age, 51.9 ± 18.33 years; range, 18-91 years] and 87 healthy volunteers) were retrieved from the company (Given Imaging, Ltd.)-sponsored database. All subjects swallowed the PillCam SB Capsule after a 12-hr fast. The capsule reached the cecum in all 877 participants. Indications for referral for capsule endoscopy were as follows: 372 obscure gastrointestinal bleeding, 96 suspected Crohn's disease, 65 celiac disease, 54 irritable bowel syndrome, and 116 familial adenomatous polyposis, intestinal lymphoma, or ulcerative colitis. One group consisted of patients <40 years old (n = 235), and the other patients 40 years old (n = 555). The younger group, volunteers, and Crohn's disease patients had significantly shorter small bowel transit times than the others (P < 0.001). Gastric emptying indirectly influenced capsule transit time.

Original languageEnglish
Pages (from-to)2884-2887
Number of pages4
JournalDigestive Diseases and Sciences
Volume52
Issue number10
DOIs
StatePublished - Oct 2007
Externally publishedYes

Keywords

  • Age
  • Capsule endoscopy
  • Gastric emptying
  • Gastrointestinal pathologies
  • Gender
  • Small bowel transit time

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