Aeruginosins from a microcystis sp. bloom material collected in Varanasi, India

Shira Elkobi-Peer, Rahul Kunwar Singh, Tribhuban Mohan Mohapatra, Shree Prakash Tiwari, Shmuel Carmeli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Two novel biologically active short peptides, aeruginosins IN608 and IN652, were isolated from the cyanobacterium Microcystis sp. strain BHU006, which was collected from Durgakund water reservoir in Varanasi, India. Aeruginosins IN608 and IN652 are linear modified peptides containing four building blocks, one of which is the arogenate-derived modified amino acid 2-carboxy-6- hydroxyoctahydroindole. Aeruginosin IN608 and aeruginosin IN652 inhibit the activity of the proteolytic enzyme trypsin with IC50's of 4.3 and 4.1 μM, respectively.

Original languageEnglish
Pages (from-to)1187-1190
Number of pages4
JournalJournal of Natural Products
Issue number6
StatePublished - 28 Jun 2013


FundersFunder number
Indian Council of Medical Research45/98/PHA/BMS


    Dive into the research topics of 'Aeruginosins from a microcystis sp. bloom material collected in Varanasi, India'. Together they form a unique fingerprint.

    Cite this