TY - JOUR
T1 - Aeruginosins from a microcystis sp. bloom material collected in Varanasi, India
AU - Elkobi-Peer, Shira
AU - Singh, Rahul Kunwar
AU - Mohapatra, Tribhuban Mohan
AU - Tiwari, Shree Prakash
AU - Carmeli, Shmuel
PY - 2013/6/28
Y1 - 2013/6/28
N2 - Two novel biologically active short peptides, aeruginosins IN608 and IN652, were isolated from the cyanobacterium Microcystis sp. strain BHU006, which was collected from Durgakund water reservoir in Varanasi, India. Aeruginosins IN608 and IN652 are linear modified peptides containing four building blocks, one of which is the arogenate-derived modified amino acid 2-carboxy-6- hydroxyoctahydroindole. Aeruginosin IN608 and aeruginosin IN652 inhibit the activity of the proteolytic enzyme trypsin with IC50's of 4.3 and 4.1 μM, respectively.
AB - Two novel biologically active short peptides, aeruginosins IN608 and IN652, were isolated from the cyanobacterium Microcystis sp. strain BHU006, which was collected from Durgakund water reservoir in Varanasi, India. Aeruginosins IN608 and IN652 are linear modified peptides containing four building blocks, one of which is the arogenate-derived modified amino acid 2-carboxy-6- hydroxyoctahydroindole. Aeruginosin IN608 and aeruginosin IN652 inhibit the activity of the proteolytic enzyme trypsin with IC50's of 4.3 and 4.1 μM, respectively.
UR - http://www.scopus.com/inward/record.url?scp=84879659695&partnerID=8YFLogxK
U2 - 10.1021/np4001152
DO - 10.1021/np4001152
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C2 - 23777401
AN - SCOPUS:84879659695
SN - 0163-3864
VL - 76
SP - 1187
EP - 1190
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 6
ER -