Adverse reactions to accidental forearm injection of bacille Calmette-Guérin vaccine in schoolchildren: 12-Month cohort follow-up

Samuel Gross; Ernesto Kahan; Liora Vesterman; Dfra Havkin; Alex Leventhál

doi:10.1086/392505

Adverse reactions to accidental forearm injection of bacille Calmette-Guérin vaccine in schoolchildren: 12-Month cohort follow-up

Samuel Gross, Ernesto Kahan^*, Liora Vesterman, Dfra Havkin, Alex Leventhál

^*Corresponding author for this work

Clinical Departments

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This study examined the natural history of reaction after accidental intradermal administration of bacille Calmette-Guérin (BCG) vaccine instead of purified protein derivative (PPD) in 226 schoolchildren. At 18 days after vaccination, a local reaction with a diameter of 4.5-14 mm was found in 62% of the students, and ulceration with discharge was found in 26.6%; corresponding rates at 120 days were 72.3% and 38% and at 281 days were 73% and 6%. At 345 days, 85% of the students had a dry scar measuring 5-14 mm in diameter, and none had ulceration or discharge.

Original language	English
Pages (from-to)	1495-1497
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	38
Issue number	10
DOIs	https://doi.org/10.1086/392505
State	Published - 15 May 2004

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AB - This study examined the natural history of reaction after accidental intradermal administration of bacille Calmette-Guérin (BCG) vaccine instead of purified protein derivative (PPD) in 226 schoolchildren. At 18 days after vaccination, a local reaction with a diameter of 4.5-14 mm was found in 62% of the students, and ulceration with discharge was found in 26.6%; corresponding rates at 120 days were 72.3% and 38% and at 281 days were 73% and 6%. At 345 days, 85% of the students had a dry scar measuring 5-14 mm in diameter, and none had ulceration or discharge.

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Adverse reactions to accidental forearm injection of bacille Calmette-Guérin vaccine in schoolchildren: 12-Month cohort follow-up

Abstract

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