Advances in the treatment of testicular cancer

Yaron Ehrlich*, David Margel, Marc Alan Lubin, Jack Baniel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented.

Original languageEnglish
Pages (from-to)381-390
Number of pages10
JournalTranslational Andrology and Urology
Volume4
Issue number3
DOIs
StatePublished - 2015

Keywords

  • Chemotherapy
  • Chemotherapy adjuvant
  • Lymph node excision
  • Neoplasm staging
  • Neoplasms germ cell tumor
  • Orchiectomy
  • Patient selection
  • Treatment outcome
  • incidence

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