Abstract
Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented.
Original language | English |
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Pages (from-to) | 381-390 |
Number of pages | 10 |
Journal | Translational Andrology and Urology |
Volume | 4 |
Issue number | 3 |
DOIs | |
State | Published - 2015 |
Keywords
- Chemotherapy
- Chemotherapy adjuvant
- Lymph node excision
- Neoplasm staging
- Neoplasms germ cell tumor
- Orchiectomy
- Patient selection
- Treatment outcome
- incidence