Advances in chronic intestinal failure management and therapies

Liat Deutsch*, Anabelle Cloutier, Simon Lal

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Purpose of reviewTo summarize changes and recent advances in therapies for chronic intestinal failure (CIF).Recent findingsIn the last few years, the management of CIF has significantly improved through better prevention and treatment of catheter-related bloodstream infections (CRBSIs) and intestinal failure-associated liver disease (IFALD), as well as improved enteral autonomy by using small bowel growth factors in selected patients. This may have been reflected by a recent reduction in small bowel transplantations.SummaryAlthough CIF management has become more established and effective, the long-term implications of parenteral nutrition still place substantial burden on patients such that further work is required to improve patients' quality of life as well as continued efforts to reduce complications relating to CIF management.

Original languageEnglish
Pages (from-to)223-229
Number of pages7
JournalCurrent Opinion in Gastroenterology
Volume36
Issue number3
DOIs
StatePublished - 1 May 2020

Keywords

  • GLP-2 analogue
  • intestinal failure
  • intestinal transplantation
  • parenteral nutrition

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