Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies

Ofer Sadan*, Estelle Seyman, Elissa L. Ash, Svetlana Kipervasser, Miri Y. Neufeld

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response to immunomodulatory treatment. The relevance of multidrug hypersensitivity in the setting of adult-onset epilepsy and the importance of searching for autoimmune causes for epilepsy are discussed.

Original languageEnglish
Pages (from-to)132-135
Number of pages4
JournalEpilepsy and Behavior Case Reports
Volume1
Issue number1
DOIs
StatePublished - Aug 2013

Keywords

  • AED
  • Hashimoto's encephalopathy
  • Hypersensitivity
  • Temporal lobe epilepsy

Fingerprint

Dive into the research topics of 'Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies'. Together they form a unique fingerprint.

Cite this