Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle

Shaul Feldman; Richard A. Siegel; Joseph Weidenfeld; Nissim Conforti; Eldad Melamed

doi:10.1016/0014-4886(84)90061-X

Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle

Shaul Feldman^*, Richard A. Siegel, Joseph Weidenfeld, Nissim Conforti, Eldad Melamed

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Adrenocortical responses, as expressed by changes in plasma corticosterone concentrations, after ether stress, or photic, acoustic, or sciatic nerve stimulation were studied in rats, with 6-hydroxydopamine or vehicle injected into the medial forebrain bundle (MFB). The neurotoxin partially inhibited the response to photic stimulation only, indicating the involvement of MFB catecholaminergic fibers in the transmission of this response which stimulates adrenocortical secretion.

Original language	English
Pages (from-to)	215-220
Number of pages	6
Journal	Experimental Neurology
Volume	83
Issue number	1
DOIs	https://doi.org/10.1016/0014-4886(84)90061-X
State	Published - Jan 1984
Externally published	Yes

Access to Document

10.1016/0014-4886(84)90061-X

Cite this

@article{416290162e8a40cfbb1f161b38d01cc1,

title = "Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle",

abstract = "Adrenocortical responses, as expressed by changes in plasma corticosterone concentrations, after ether stress, or photic, acoustic, or sciatic nerve stimulation were studied in rats, with 6-hydroxydopamine or vehicle injected into the medial forebrain bundle (MFB). The neurotoxin partially inhibited the response to photic stimulation only, indicating the involvement of MFB catecholaminergic fibers in the transmission of this response which stimulates adrenocortical secretion.",

author = "Shaul Feldman and Siegel, {Richard A.} and Joseph Weidenfeld and Nissim Conforti and Eldad Melamed",

note = "Funding Information: Abbreviations: MFB-medial forebrain bundle, 6-OHDA-6-hydroxydopamine, ACTH-adrenocorticotrophic hormone, NE-norepinephrine, MBH-mediobasal hypothalamic. i This research has been supported by The Fund for Basic Research Administered by the Israel Academy of Sciences and Humanities. The technical assistance of A. Izik, E. Reinhartz, and A. Uzzan, is gratefully acknowledged. Please send correspondence to Dr. Feldman, Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.",

year = "1984",

month = jan,

doi = "10.1016/0014-4886(84)90061-X",

language = "אנגלית",

volume = "83",

pages = "215--220",

journal = "Experimental Neurology",

issn = "0014-4886",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle

AU - Feldman, Shaul

AU - Siegel, Richard A.

AU - Weidenfeld, Joseph

AU - Conforti, Nissim

AU - Melamed, Eldad

N1 - Funding Information: Abbreviations: MFB-medial forebrain bundle, 6-OHDA-6-hydroxydopamine, ACTH-adrenocorticotrophic hormone, NE-norepinephrine, MBH-mediobasal hypothalamic. i This research has been supported by The Fund for Basic Research Administered by the Israel Academy of Sciences and Humanities. The technical assistance of A. Izik, E. Reinhartz, and A. Uzzan, is gratefully acknowledged. Please send correspondence to Dr. Feldman, Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.

PY - 1984/1

Y1 - 1984/1

N2 - Adrenocortical responses, as expressed by changes in plasma corticosterone concentrations, after ether stress, or photic, acoustic, or sciatic nerve stimulation were studied in rats, with 6-hydroxydopamine or vehicle injected into the medial forebrain bundle (MFB). The neurotoxin partially inhibited the response to photic stimulation only, indicating the involvement of MFB catecholaminergic fibers in the transmission of this response which stimulates adrenocortical secretion.

AB - Adrenocortical responses, as expressed by changes in plasma corticosterone concentrations, after ether stress, or photic, acoustic, or sciatic nerve stimulation were studied in rats, with 6-hydroxydopamine or vehicle injected into the medial forebrain bundle (MFB). The neurotoxin partially inhibited the response to photic stimulation only, indicating the involvement of MFB catecholaminergic fibers in the transmission of this response which stimulates adrenocortical secretion.

UR - http://www.scopus.com/inward/record.url?scp=0021323962&partnerID=8YFLogxK

U2 - 10.1016/0014-4886(84)90061-X

DO - 10.1016/0014-4886(84)90061-X

M3 - מאמר

AN - SCOPUS:0021323962

VL - 83

SP - 215

EP - 220

JO - Experimental Neurology

JF - Experimental Neurology

SN - 0014-4886

IS - 1

ER -

Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle

Abstract

Access to Document

Other files and links

Fingerprint

Cite this