Adiponectin and human pregnancy

Shali Mazaki-Tovi, Hannah Kanety, Eyal Sivan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Adiponectin is an adipose tissue-derived plasma protein that is involved in regulation of insulin resistance and glucose hemostasis. Human pregnancy is characterized by an increase in insulin resistance. Therefore, it is only natural that the role of adiponectin, a modulator of insulin resistance, is subject to investigation during gestation. Furthermore, conditions associated with increased insulin resistance, such as gestational diabetes and preeclampsia, may be influenced by this hormone. Adiponectin, a key modulator of insulin action and glucose metabolism, both known to regulate fetal growth, is a plausible candidate for regulation of intrauterine fetal development. In this review, we summarize the recent studies describing the relationship between adiponectin, pregnancy, and fetal growth.

Original languageEnglish
Pages (from-to)278-281
Number of pages4
JournalCurrent Diabetes Reports
Issue number4
StatePublished - Aug 2005


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