Adhesion of non-coccal dental plaque microorganisms to buccal epithelial cells: Inhibition by saliva and amphipathic agents

Mel Rosenberg*, Meir Tal, Ervin Weiss, Sergio Guendelman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In the present investigation, the in vitro adhesion of dispersed non-coccal dental plaque bacteria to buccal epithelial cells was examined. Human buccal epithelial cells, incubated in the presence of dispersed supragingival dental plaque, bound averages of ca. 6-15 non-coccal forms/epithelial cell, as opposed to indigenous levels of only 0.2-0.6 on buccal epithelial cells incubated in buffer alone. Adhesion was strongly inhibited by amphipathic agents (Tween 80, sodium dodecyl sulphate, and emulsan), and by saliva. The data suggests firstly that non-coccal bacteria can adhere to epithelial cells in vitro, but may be prevented from doing so in situ by saliva, and secondly that hydrophobic interactions may help mediate the observed adhesion.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalMicrobial Ecology in Health and Disease
Volume2
Issue number3
DOIs
StatePublished - 1989

Keywords

  • Adhesion
  • Amphipathic agents
  • Dental plaque
  • Epithelial cells
  • Saliva

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