ADHD as a Risk Factor for Infection With Covid-19

Eugene Merzon, Iris Manor*, Ann Rotem, Tzipporah Schneider, Shlomo Vinker, Avivit Golan Cohen, Ari Lauden, Abraham Weizman, Ilan Green

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: ADHD limits the ability to comply with Covid-19 prevention recommendations. We hypothesized that ADHD constitutes a risk factor for Covid-19 infection and that pharmacotherapy may lower that risk. Methods: Study population included all subjects (N = 14,022) registered with Leumit Health Services between February 1st and April 30, 2020, who underwent at least one Covid-19 test. Data were collected from the electronic health records. Purchasing consecutively at least three ADHD-medication-prescriptions during past year was considered drug-treatment. Results: A total of 1,416 (10.1%) subjects (aged 2 months–103 years) were Covid-19-positive.They were significantly younger, and had higher rates of ADHD (adjOR 1.58 (95% CI 1.27–1.96, p <.001) than Covid-19-negative subjects. The risk for Covid-19-Positive was higher in untreated-ADHD subjects compared to non-ADHD subjects [crudeOR 1.61 (95% CI 1.36–1.89, p <.001)], while no higher risk was detected in treated ones [crudeOR 1.07 (95% CI 0.78–1.48, p =.65)]. Conclusion: Untreated ADHD seems to constitute a risk factor for Covid-19 infection while drug-treatment ameliorates this effect.

Original languageEnglish
Pages (from-to)1783-1790
Number of pages8
JournalJournal of Attention Disorders
Volume25
Issue number13
DOIs
StatePublished - Nov 2021

Keywords

  • ADHD
  • Covid-19
  • prevalence
  • stimulants

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