Addition of bone marrow aspirate concentrate resulted in high rate of healing and good functional outcomes in the treatment of clavicle fracture nonunion: A retrospective case series

Dvir Benshabat, Shai Factor, Eran Maman, Amal Khoury, Raphael Krespi, Itay Ashkenazi, Ofir Chechik, Oleg Dolkart

Research output: Contribution to journalArticlepeer-review

Abstract

Bone marrow aspirate concentrate (BMAC) is an autologous cell composition that is obtained through a needle aspiration from the iliac crest. The purpose of this study was to evaluate the outcomes of patients treated with open reduction and internal fixation with BMAC supplementation for clavicle fracture nonunion. This was a retrospective case series of 21 consecutive patients with clavicle fracture nonunion that were treated with ORIF and BMAC supplementation between 2013 and 2020. Patients were evaluated for fracture union, time to union, complications related to surgical and donor site, and functional outcome using the Quick Disability of the Arm Shoulder and Hand (QDASH), subjective shoulder value (SSV), and pain. The mean age was 41.8 years. The mean follow-up was 36 months. Twenty (95.2%) patients demonstrated fracture union, with a mean time to union of 4.5 months. Good functional scores were achieved: SSV, 74.3; QDASH, 23.3; pain level, 3.1. There were no complications or pain related to the iliac crest donor site. Supplementary BMAC to ORIF in the treatment of clavicle fracture nonunion is a safe method, resulting in high rates of fracture union and good functional outcomes with minimal complications and pain.

Original languageEnglish
Article number4749
JournalJournal of Clinical Medicine
Volume10
Issue number20
DOIs
StatePublished - 1 Oct 2021
Externally publishedYes

Keywords

  • BMAC
  • Bone marrow aspirate concentrate
  • Clavicle fracture
  • Internal fixation
  • Nonunion
  • Open reduction

Fingerprint

Dive into the research topics of 'Addition of bone marrow aspirate concentrate resulted in high rate of healing and good functional outcomes in the treatment of clavicle fracture nonunion: A retrospective case series'. Together they form a unique fingerprint.

Cite this