Abstract
In this study, a mathematical model of a single trabecula was developed to simulate its long-term adaptive response in a changing stress environment. The model incorporates an osteocyte mechanosensing network that regulates the morphology and tissue material behavior of the trabecula. The adaptation response was shown to be most sensitive to changes in bending moments acting on the trabecula's boundaries, and a decrease of more than 57% in their value caused thinning of the trabecular profiles.
Original language | English |
---|---|
Pages (from-to) | 458-459 |
Number of pages | 2 |
Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
Volume | 1 |
State | Published - 2002 |
Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: 23 Oct 2002 → 26 Oct 2002 |
Keywords
- Cancellous bone remodeling
- Mechanosensing
- Model