TY - JOUR
T1 - Adalimumab-induced Autoimmune Hepatitis
AU - Adar, Tomer
AU - Mizrahi, Meir
AU - Pappo, Orit
AU - Scheiman-Elazary, Anat
AU - Shibolet, Oren
PY - 2010/1
Y1 - 2010/1
N2 - Antitumor necrosis factor antibodies are widely used in the treatment of autoimmune diseases. We describe the occurrence of autoimmune hepatitis in a patient treated with adalimumab, a fully human IgG antibody against tumor necrosis factor, for psoriatic arthritis. The patient made a full recovery after discontinuation of adalimumab and treatment with steroids. This is the first reported case of adalimumab-induced autoimmune hepatitis.
AB - Antitumor necrosis factor antibodies are widely used in the treatment of autoimmune diseases. We describe the occurrence of autoimmune hepatitis in a patient treated with adalimumab, a fully human IgG antibody against tumor necrosis factor, for psoriatic arthritis. The patient made a full recovery after discontinuation of adalimumab and treatment with steroids. This is the first reported case of adalimumab-induced autoimmune hepatitis.
KW - Adalimumab
KW - Anti-TNF
KW - Autoimmune hepatitis
UR - http://www.scopus.com/inward/record.url?scp=75149157116&partnerID=8YFLogxK
U2 - 10.1097/MCG.0b013e3181a745e7
DO - 10.1097/MCG.0b013e3181a745e7
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C2 - 19593165
AN - SCOPUS:75149157116
SN - 0192-0790
VL - 44
SP - e20-e22
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
IS - 1
ER -