Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy

Constantin Sylantiev; Nili Schoenfeld; Rivka Mamet; Galina B. Groozman; Vivian E. Drory

doi:10.1002/mus.20167

Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy

Constantin Sylantiev, Nili Schoenfeld, Rivka Mamet, Galina B. Groozman, Vivian E. Drory^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

An 82-year-old man developed severe, acute, predominantly motor polyneuropathy, signs of autonomic involvement, and skin changes following aminolevulinic acid (ALA) administration. The compound was used as a prodrug for photodynamic therapy of Barrett's esophagitis. Changes were observed in various parameters of the heme pathway. The case reported represents a rare response to ALA treatment, resembling an acute attack of hepatic porphyria with neurological features.

Original language	English
Pages (from-to)	390-393
Number of pages	4
Journal	Muscle and Nerve
Volume	31
Issue number	3
DOIs	https://doi.org/10.1002/mus.20167
State	Published - Mar 2005

Keywords

Aminolevulinic acid
Photodynamic therapy
Polyneuropathy
Porphyria

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10.1002/mus.20167

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title = "Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy",

abstract = "An 82-year-old man developed severe, acute, predominantly motor polyneuropathy, signs of autonomic involvement, and skin changes following aminolevulinic acid (ALA) administration. The compound was used as a prodrug for photodynamic therapy of Barrett's esophagitis. Changes were observed in various parameters of the heme pathway. The case reported represents a rare response to ALA treatment, resembling an acute attack of hepatic porphyria with neurological features.",

keywords = "Aminolevulinic acid, Photodynamic therapy, Polyneuropathy, Porphyria",

author = "Constantin Sylantiev and Nili Schoenfeld and Rivka Mamet and Groozman, {Galina B.} and Drory, {Vivian E.}",

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AU - Sylantiev, Constantin

AU - Schoenfeld, Nili

AU - Mamet, Rivka

AU - Groozman, Galina B.

AU - Drory, Vivian E.

PY - 2005/3

Y1 - 2005/3

N2 - An 82-year-old man developed severe, acute, predominantly motor polyneuropathy, signs of autonomic involvement, and skin changes following aminolevulinic acid (ALA) administration. The compound was used as a prodrug for photodynamic therapy of Barrett's esophagitis. Changes were observed in various parameters of the heme pathway. The case reported represents a rare response to ALA treatment, resembling an acute attack of hepatic porphyria with neurological features.

AB - An 82-year-old man developed severe, acute, predominantly motor polyneuropathy, signs of autonomic involvement, and skin changes following aminolevulinic acid (ALA) administration. The compound was used as a prodrug for photodynamic therapy of Barrett's esophagitis. Changes were observed in various parameters of the heme pathway. The case reported represents a rare response to ALA treatment, resembling an acute attack of hepatic porphyria with neurological features.

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KW - Photodynamic therapy

KW - Polyneuropathy

KW - Porphyria

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Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy

Abstract

Keywords

UN SDGs

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