TY - JOUR
T1 - Acute mastoiditis before pneumococcal vaccination
T2 - The experience of a large tertiary care pediatric hospital
AU - Glatstein, Miguel
AU - Morag, Sharon
AU - Scolnik, Dennis
AU - Alper, Arik
AU - Reif, Shimon
AU - Grisaru-Soen, Galia
N1 - Publisher Copyright:
Copyright © 2015 Wolters Kluwer Health, Inc.
PY - 2016/11/28
Y1 - 2016/11/28
N2 - To report the experience of a large tertiary care pediatric center during a period of increasing Streptococcus pneumoniae antimicrobial resistance before the introduction of pneumococcal vaccine in Israel. Retrospective chart review of children diagnosed acute mastoiditis (AM) between January 1997 and December 2007. The children were divided into 4 age groups (6-11, 12-23, 24-35, and 36-40 months), and each group was compared with the others. A total of 198 AM episodes were recorded during the 10-year study period. The most prevalent pathogen was S. pneumonia, with a very low (15%) penicillin resistance rate (minimal inhibitory concentration 2). Complications were more prevalent in the 12-to 23-month age group. The number of AM cases increased during the study period. Penicillin resistance did not play an important role in determining the morbidity before the introduction of pneumococcal conjugate vaccine.
AB - To report the experience of a large tertiary care pediatric center during a period of increasing Streptococcus pneumoniae antimicrobial resistance before the introduction of pneumococcal vaccine in Israel. Retrospective chart review of children diagnosed acute mastoiditis (AM) between January 1997 and December 2007. The children were divided into 4 age groups (6-11, 12-23, 24-35, and 36-40 months), and each group was compared with the others. A total of 198 AM episodes were recorded during the 10-year study period. The most prevalent pathogen was S. pneumonia, with a very low (15%) penicillin resistance rate (minimal inhibitory concentration 2). Complications were more prevalent in the 12-to 23-month age group. The number of AM cases increased during the study period. Penicillin resistance did not play an important role in determining the morbidity before the introduction of pneumococcal conjugate vaccine.
KW - Acute mastoiditis
KW - Otitis media
KW - Pediatric
KW - Penicillin resistance
KW - Streptococcus pneumonia
UR - http://www.scopus.com/inward/record.url?scp=84916209702&partnerID=8YFLogxK
U2 - 10.1097/MJT.0000000000000097
DO - 10.1097/MJT.0000000000000097
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C2 - 25285797
AN - SCOPUS:84916209702
SN - 1075-2765
VL - 23
SP - e1371-e1374
JO - American Journal of Therapeutics
JF - American Journal of Therapeutics
IS - 6
ER -
