Acute mania and hemichorea

Rivka Inzelberg*, Puiu Nisipeanu, Daphna Joel, Martha Sarkantyus, Ralph L. Carasso

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A 61-year-old man suddenly became euphoric and talkative. Later the same day, he developed hemichoreic movements of the left limbs. The patient fulfilled the DSM-IV criteria for a manic episode by abnormally and persistently elevated mood, decreased need for sleep, high distractibility, pressured speech, increased goal-directed activity, and hypersexuality. The mood changes persisted for several weeks. Magnetic resonance imaging of the brain showed a right thalamic infarction. The co-occurrence of hemichorea and mania caused by focal thalamic lesion is very rare. It may be explained by dysfunction in basal ganglia thalamocortical circuitry.

Original languageEnglish
Pages (from-to)300-303
Number of pages4
JournalClinical Neuropharmacology
Issue number5
StatePublished - 2001


  • Basal ganglia
  • Chorea
  • Mania
  • Thalamus


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