Acute hepatic failure after open-heart surgery in children

Yakov Sivan, Jacob Nutman, Benjamin Zeevi, Michael Berant, Leon Levinsky, Tommy Schonfeld

Research output: Contribution to journalArticlepeer-review


Acute hepatic failure (AHF) combined with acute renal failure (ARF) is a well-known complication of open-heart surgery in adults. The occurrence of this complication in two children after open-heart surgery for correction of congenital heart disease is reported. Hypotension occurred during the operation and was treated by catecholamine vasopressors. AHF set in during the postoperative course; it was manifested by impaired consciousness, hypoglycemia, hyperbilirubinemia, hyperammonemia, elevated liver enzymes and prolongation of the prothrombin time with failure of hemostasis. ARF also developed in both children. One of the patients survived the acute episode of hepatic failure. The importance of early diagnosis, routine close monitoring, and appropriate selection of vasopressors is emphasized.

Original languageEnglish
Pages (from-to)127-130
Number of pages4
JournalPediatric Cardiology
Issue number2
StatePublished - Jun 1987


  • Acute hepatic failure
  • Acute renal failure
  • Catecholamines
  • Open-heart surgery
  • Shock


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