Abstract
The effect of prior incubation with a single concentration of isoproterenol (10-4 M) for 2 hours at 37°C on isoproterenol-stimulated cyclic AMP accumulation in intact lymphocytes from young, old and subjects with Alzheimer's disease was studied. In lymphocytes from all three subject groups prior incubation of cells with isoproterenol resulted in a significant reduction of cyclic AMP accumulation upon subsequent stimulation with isoproterenol.
Original language | English |
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Pages (from-to) | 1795-1802 |
Number of pages | 8 |
Journal | Life Sciences |
Volume | 35 |
Issue number | 17 |
DOIs | |
State | Published - 22 Oct 1984 |
Externally published | Yes |