Active particle based selective transport and release of cell organelles and mechanical probing of a single nucleus

Yue Wu, Afu Fu, Gilad Yossifon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We applied a mobile floating microelectrode to trap and transport cell organelles in a selective and releasable manner. This selectivity is driven by the different dielectrophoretic (DEP) potential wells on the JP surface that are controlled by the frequency of the electric field, along with the hydrodynamic shearing and size of the trapped organelles. Hence, the active carrier constitutes an important and novel ex vivo platform for manipulation and mechanical probing of subcellular components of potential for single cell analysis.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages829-830
Number of pages2
ISBN (Electronic)9781733419017
StatePublished - 2020
Externally publishedYes
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 4 Oct 20209 Oct 2020

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period4/10/209/10/20

Keywords

  • Active particle
  • Cell organelles
  • Dielectrophoretic
  • Electro-deformation

Fingerprint

Dive into the research topics of 'Active particle based selective transport and release of cell organelles and mechanical probing of a single nucleus'. Together they form a unique fingerprint.

Cite this