Acral angiokeratoma-like pseudolymphoma in a middle-aged woman

Shamir Geller, Alina Markova, Melissa Pulitzer, Patricia L. Myskowski

Research output: Contribution to journalArticlepeer-review

Abstract

Acral angiokeratoma-like pseudolymphoma is a rare type of pseudolymphoma presenting as dark-red papules on the hand or foot. We describe a 59-year-old woman who presented with an unusual unilateral, clustered aggregate of scaly violaceous papules on the toe with an indolent course. Skin biopsy showed a prominent vascular proliferation associated with a dermal infiltrate of monoclonally rearranged T-follicular helper phenotype T-cells, in keeping with CD4+ small/medium T-cell lymphoproliferative disorder (SMPTC-LPD). Based on the unique clinical morphology, distribution of the lesions and dermoscopic appearance, a clinicopathologic diagnosis of acral angiokeratoma-like pseudolymphoma was favored. This case demonstrates the importance of clinicopathological correlation in such diagnostically challenging patients who present with overlapping features on the spectrum of pseudolymphoma and cutaneous T-cell lymphoma.

Original languageEnglish
Pages (from-to)878-881
Number of pages4
JournalJournal of Cutaneous Pathology
Volume44
Issue number10
DOIs
StatePublished - Oct 2017
Externally publishedYes

Keywords

  • cutaneous T-cell lymphoma
  • pseudolymphoma
  • skin cancer

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