Accumulation of c-src mRNA is developmentally regulated in embryonic neural retina.

L. Vardimon*, L. E. Fox, A. A. Moscona

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Accumulation of c-src mRNA gradually increased during early development of the neural retina in chicken embryos and reached a peak by days 11 to 13 of embryonic life. Thereafter, its amount declined to a low level which persisted also in adult retina. The early increase in c-src mRNA correlated inversely with the decrease in the amount of H3.2 replication histone mRNA and with the decline in the rate of cell growth. The accumulation profile of c-src mRNA corresponded to that of pp60c-src protein, suggesting that the latter is regulated at the level of transcription.

Original languageEnglish
Pages (from-to)4109-4111
Number of pages3
JournalMolecular and Cellular Biology
Volume6
Issue number11
DOIs
StatePublished - Nov 1986

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