Accelerated atheroma, antiphospholipid antibodies, and the antiphospholipid syndrome

Jacob George, Dror Haratz, Yehuda Shoenfeld*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Indirect data coming from animal studies and in vitro observations support the contention that the mere presence of antiphospholipid antibodies may be sufficient to increase antheroma development, regardless of other predisposing factors. It seems that humoral and cellular immune responses to β2-glycoprotein I can play ab important role in mediating the increased prospensity to atherosclerosis.

Original languageEnglish
Pages (from-to)603-610
Number of pages8
JournalRheumatic Disease Clinics of North America
Issue number3
StatePublished - 2001
Externally publishedYes


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