Immunology is a relatively new specialty. Ironically, the immune system impacts every physiological system in the body, but yet most textbooks of physiology do not include any functional aspects of the immune system. Indeed, with the exception of early descriptions of anaphylaxis and allergy, the majority of immune studies were focused on either the anatomy of lymph nodes and spleen, or of course on protection from microorganisms. The concept of autoimmunity is even newer and the first textbook on autoimmune disease was not published until 1963. For the past 50 years however, autoimmunity has virtually exploded from a field populated by a few, to recognition that autoimmune diseases can affect more than 10% of the population. There are many people that have contributed to this information explosion and the Journal of Autoimmunity devotes specific issues in recognition of the select few scientists that have contributed in a way that impacts not only their research peers, but also, and more importantly, the patients who suffer from autoimmune disease. Abul Abbas is one such individual. Abul is known not only for his outstanding research, but for his role in teaching and public service. His own scientific work is extraordinary and his impact is felt throughout the world. In this special issue a number of Abul's colleagues have specifically written papers to honor this unique individual. It is an extraordinary honor to be chosen for a special issue of a journal in recognition of one's career.
- Immune regulation
- T cell subsets