Abnormal thermoregulation in drug-free male schizophrenia patients

Roni Shiloh; Abraham Weizman; Yoram Epstein; Sara Lea Rosenberg; Avi Valevski; Pnina Dorfman-Etrog; Nehama Wiezer; Nachum Katz; Hanan Munitz; Haggai Hermesh

doi:10.1016/S0924-977X(01)00096-7

Abnormal thermoregulation in drug-free male schizophrenia patients

Roni Shiloh, Abraham Weizman^*, Yoram Epstein, Sara Lea Rosenberg, Avi Valevski, Pnina Dorfman-Etrog, Nehama Wiezer, Nachum Katz, Hanan Munitz, Haggai Hermesh

^*Corresponding author for this work

Clinical Departments

Geha Mental Health Center

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

Schizophrenia patients may develop various thermoregulatory disturbances. We hypothesized that a standardized exercise-heat tolerance test [two 50-min bouts of walking a motor-driven treadmill at 40°C (relative humidity=40%)] would reveal abnormal thermoregulation in drug-free schizophrenia patients. Six drug-free schizophrenia outpatients and seven healthy comparison subjects participated in this study. The schizophrenia patients exhibited significantly higher baseline and exertion-related rectal temperature. The relevance of these findings to the pathophysiology of schizophrenia-related thermoregulatory disorders is as yet unclear.

Original language	English
Pages (from-to)	285-288
Number of pages	4
Journal	European Neuropsychopharmacology
Volume	11
Issue number	4
DOIs	https://doi.org/10.1016/S0924-977X(01)00096-7
State	Published - 2001

Keywords

Heat-stress
Schizophrenia
Thermoregulation

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title = "Abnormal thermoregulation in drug-free male schizophrenia patients",

abstract = "Schizophrenia patients may develop various thermoregulatory disturbances. We hypothesized that a standardized exercise-heat tolerance test [two 50-min bouts of walking a motor-driven treadmill at 40°C (relative humidity=40%)] would reveal abnormal thermoregulation in drug-free schizophrenia patients. Six drug-free schizophrenia outpatients and seven healthy comparison subjects participated in this study. The schizophrenia patients exhibited significantly higher baseline and exertion-related rectal temperature. The relevance of these findings to the pathophysiology of schizophrenia-related thermoregulatory disorders is as yet unclear.",

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AU - Shiloh, Roni

AU - Weizman, Abraham

AU - Epstein, Yoram

AU - Rosenberg, Sara Lea

AU - Valevski, Avi

AU - Dorfman-Etrog, Pnina

AU - Wiezer, Nehama

AU - Katz, Nachum

AU - Munitz, Hanan

AU - Hermesh, Haggai

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Y1 - 2001

N2 - Schizophrenia patients may develop various thermoregulatory disturbances. We hypothesized that a standardized exercise-heat tolerance test [two 50-min bouts of walking a motor-driven treadmill at 40°C (relative humidity=40%)] would reveal abnormal thermoregulation in drug-free schizophrenia patients. Six drug-free schizophrenia outpatients and seven healthy comparison subjects participated in this study. The schizophrenia patients exhibited significantly higher baseline and exertion-related rectal temperature. The relevance of these findings to the pathophysiology of schizophrenia-related thermoregulatory disorders is as yet unclear.

AB - Schizophrenia patients may develop various thermoregulatory disturbances. We hypothesized that a standardized exercise-heat tolerance test [two 50-min bouts of walking a motor-driven treadmill at 40°C (relative humidity=40%)] would reveal abnormal thermoregulation in drug-free schizophrenia patients. Six drug-free schizophrenia outpatients and seven healthy comparison subjects participated in this study. The schizophrenia patients exhibited significantly higher baseline and exertion-related rectal temperature. The relevance of these findings to the pathophysiology of schizophrenia-related thermoregulatory disorders is as yet unclear.

KW - Heat-stress

KW - Schizophrenia

KW - Thermoregulation

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Abnormal thermoregulation in drug-free male schizophrenia patients

Abstract

Keywords

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