Abnormal Fluid, Electrolyte, and Acid-Base Regulation in an Infant with Congenital Hypopituitarism

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Abstract

A male infant, who initially presented with hypernatraemia and hypercalcaemia, was subsequently found to have central diabetes insipidus, hypoadrenalism and hypothyroidism. Neuro-endocrine evaluation suggested a hypothalamic or combined hypothalamic-pituitary defect. Computerized tomography of the septum pellucidum was normal. Abnormal water and electrolyte homeostasis and proximal renal tubular acidosis were corrected by hormone replacement therapy.

Original languageEnglish
Pages (from-to)205-208
Number of pages4
JournalJournal of Pediatric Endocrinology and Metabolism
Volume2
Issue number4
DOIs
StatePublished - Oct 1987

Keywords

  • Hypernatraemia
  • Hypothalamic neuroendocrine abnormalities
  • Proximal renal tubular acidosis

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