TY - JOUR
T1 - Abdominopelvic irradiation for stage II-IV ovarian carcinoma patients with limited or no residual disease at second-look laparotomy after completion of cisplatinum-based combination chemotherapy
AU - Menczer, J.
AU - Modan, M.
AU - Brenner, J.
AU - Ben-Baruch, G.
AU - Brenner, H.
PY - 1986/6
Y1 - 1986/6
N2 - Abdominopelvic irradiation was given to 18 stage II-IV ovarian carcinoma patients who completed cisplatinum-based combination chemotherapy, were in complete clinical remission, and who underwent second-look laparotomy. The survival as well as the progression-free interval (PFI) was significantly longer in patients with a negative second-look laparotomy than in those with limited residual disease at this operation. Abdominopelvic irradiation was not effective in patients with limited residual disease at second-look laparotomy (3 year survival-34.3% and median PFI from second-look laparotomy-4.8 months). Even in patients with a negative second-look laparotomy the median PFI was only 13 months from this operation and the 3-year survival was 87.5%. The results were similar to other comparable series in which no treatment was administered to patients with a negative second-look laparotomy.
AB - Abdominopelvic irradiation was given to 18 stage II-IV ovarian carcinoma patients who completed cisplatinum-based combination chemotherapy, were in complete clinical remission, and who underwent second-look laparotomy. The survival as well as the progression-free interval (PFI) was significantly longer in patients with a negative second-look laparotomy than in those with limited residual disease at this operation. Abdominopelvic irradiation was not effective in patients with limited residual disease at second-look laparotomy (3 year survival-34.3% and median PFI from second-look laparotomy-4.8 months). Even in patients with a negative second-look laparotomy the median PFI was only 13 months from this operation and the 3-year survival was 87.5%. The results were similar to other comparable series in which no treatment was administered to patients with a negative second-look laparotomy.
UR - http://www.scopus.com/inward/record.url?scp=0022527014&partnerID=8YFLogxK
U2 - 10.1016/0090-8258(86)90021-1
DO - 10.1016/0090-8258(86)90021-1
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AN - SCOPUS:0022527014
SN - 0090-8258
VL - 24
SP - 149
EP - 154
JO - Gynecologic Oncology
JF - Gynecologic Oncology
IS - 2
ER -
