Abstract
The routine detection, surveillance, and reporting of novel SARS-CoV-2 variants is crucial, as these threaten to hinder global vaccination efforts. Herein we report a novel local variant with a non-synonymous mutation in the spike (S) protein P681H. This local Israeli variant was not associated with a higher infection rate or higher prevalence. Furthermore, the local variant was successfully neutralized by sera from fully vaccinated individuals at a comparable level to the B.1.1.7 variant and an Israel wild-type strain. While it is not a variant of concern, routine monitoring by sequencing is still required.
Original language | English |
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Article number | 616 |
Journal | Vaccines |
Volume | 9 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2021 |
Keywords
- Covid-19
- SARS-CoV-2
- Sequencing
- Variant of concern
- Virus neutralization