A systematic review of precipitating physical and psychological traumatic events in the development of fibromyalgia

Yarden Yavne, Daniela Amital, Abdulla Watad, Shmuel Tiosano, Howard Amital*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The role of physical and psychological trauma precipitating fibromyalgia is often encountered by physicians, yet a proper systematical review of this association is lacking. Literature searches identified 51 studies which examined the association of fibromyalgia with a preceding traumatic event of physical or emotional nature. The overall quality of evidence of studies included, as assessed by the GRADE criteria, was low, however the majority of studies described a significant association between prior physically traumatic events and the onset of chronic widespread pain or fibromyalgia. Elevated rates of psychological trauma in fibromyalgia patients were demonstrated across the literature and several studies indicate a mediating effect of post-traumatic stress disorder. Potential biological mechanisms for conversion of traumatic events into a chronic pain syndrome, such as fibromyalgia, are discussed.

Original languageEnglish
Pages (from-to)121-133
Number of pages13
JournalSeminars in Arthritis and Rheumatism
Volume48
Issue number1
DOIs
StatePublished - Aug 2018

Keywords

  • fibromyalgia
  • injury
  • psychological
  • trauma
  • trigger

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