A precipitation event of unprecedented intensity took place over northern part of Israel during 4 December 2001-5 December 2001. The case was associated with formation of a Cyprus Low cyclone over the Asia Minor. In the current study the synoptic developments over the eastern part of the Mediterranean region are simulated with the MM5 nonhydrostatic model and analyzed based on dynamic tropopause patterns calculated from the simulation results. According to the results, a powerful potential vorticity (PV) streamer system played a major role in the process over the southeastern Mediterranean region. The PV streamer created conditions for seclusion of moist air masses from the equatorial East Africa and Atlantics during the cyclone development. Condensation of the moisture, associated with the latent heat release processes have contributed to the intense thunderstorm activity and heavy precipitation of the event.