A small molecule peptidomimetic of spider silk and webs

Krishnendu Maji, Rajib Sarkar, Santu Bera, Debasish Haldar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A peptidomimetic compound containing leucine, tyrosine and malonic acid self-assembles through various noncovalent interactions to form spider silk-like fibers at ambient temperature. From the high-density liquid, a liquid-solid phase transition is initiated at 20 °C and solidification occurs upon contact with air. The fiber has comprehensive mechanical strength and optical properties similar to spider silk, and can be used to mimic a natural spider web.

Original languageEnglish
Pages (from-to)12749-12752
Number of pages4
JournalChemical Communications
Issue number84
StatePublished - 25 Sep 2014
Externally publishedYes


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