A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit

Ronella Marom; Ronella Marom; Dror Mandel; Dror Mandel; Alon Haham; Alon Haham; Irit Berger; Irit Berger; Amit Ovental; Amit Ovental; Craig Raskind; Craig Raskind; Galia Grisaru-Soen; Galia Grisaru-Soen; Amos Adler; Amos Adler; Jonathan Lellouche; David Schwartz; Yehuda Carmeli; Yehuda Carmeli; Yehuda Carmeli; Vered Schechner; Vered Schechner

doi:10.1186/s13756-020-00755-0

A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit

Ronella Marom^*, Ronella Marom^*, Dror Mandel, Dror Mandel, Alon Haham, Alon Haham, Irit Berger, Irit Berger, Amit Ovental, Amit Ovental, Craig Raskind, Craig Raskind, Galia Grisaru-Soen, Galia Grisaru-Soen, Amos Adler, Amos Adler, Jonathan Lellouche, David Schwartz, Yehuda Carmeli, Yehuda CarmeliYehuda Carmeli, Vered Schechner, Vered Schechner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Objective: To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU). Methods: Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients. Results: A newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified. Conclusion: Our study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU's routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.

Original language	English
Article number	87
Journal	Antimicrobial Resistance and Infection Control
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/s13756-020-00755-0
State	Published - 16 Jun 2020

Keywords

Infection
Neonatal intensive care unit
Neonate
Outbreak
Screening
Vancomycin-resistant Enterococcus faecium

Access to Document

10.1186/s13756-020-00755-0

Cite this

Marom, R., Marom, R., Mandel, D., Mandel, D., Haham, A., Haham, A., Berger, I., Berger, I., Ovental, A., Ovental, A., Raskind, C., Raskind, C., Grisaru-Soen, G., Grisaru-Soen, G., Adler, A., Adler, A., Lellouche, J., Schwartz, D., Carmeli, Y., ... Schechner, V. (2020). A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit. Antimicrobial Resistance and Infection Control, 9(1), Article 87. https://doi.org/10.1186/s13756-020-00755-0

@article{b8899484b125461186ae8e2bb1cd25a7,

title = "A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit",

abstract = "Objective: To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU). Methods: Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients. Results: A newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified. Conclusion: Our study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU's routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.",

keywords = "Infection, Neonatal intensive care unit, Neonate, Outbreak, Screening, Vancomycin-resistant Enterococcus faecium",

author = "Ronella Marom and Ronella Marom and Dror Mandel and Dror Mandel and Alon Haham and Alon Haham and Irit Berger and Irit Berger and Amit Ovental and Amit Ovental and Craig Raskind and Craig Raskind and Galia Grisaru-Soen and Galia Grisaru-Soen and Amos Adler and Amos Adler and Jonathan Lellouche and David Schwartz and Yehuda Carmeli and Yehuda Carmeli and Yehuda Carmeli and Vered Schechner and Vered Schechner",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s).",

year = "2020",

month = jun,

day = "16",

doi = "10.1186/s13756-020-00755-0",

language = "אנגלית",

volume = "9",

journal = "Antimicrobial Resistance and Infection Control",

issn = "2047-2994",

publisher = "BioMed Central Ltd.",

number = "1",

}

Marom, R , Marom, R , Mandel, D , Mandel, D, Haham, A, Haham, A, Berger, I, Berger, I, Ovental, A, Ovental, A, Raskind, C, Raskind, C, Grisaru-Soen, G , Grisaru-Soen, G , Adler, A , Adler, A, Lellouche, J, Schwartz, D, Carmeli, Y , Carmeli, Y , Carmeli, Y , Schechner, V & Schechner, V 2020, 'A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit', Antimicrobial Resistance and Infection Control, vol. 9, no. 1, 87. https://doi.org/10.1186/s13756-020-00755-0

TY - JOUR

T1 - A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit

AU - Marom, Ronella

AU - Mandel, Dror

AU - Haham, Alon

AU - Berger, Irit

AU - Ovental, Amit

AU - Raskind, Craig

AU - Grisaru-Soen, Galia

AU - Adler, Amos

AU - Lellouche, Jonathan

AU - Schwartz, David

AU - Carmeli, Yehuda

AU - Schechner, Vered

PY - 2020/6/16

Y1 - 2020/6/16

N2 - Objective: To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU). Methods: Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients. Results: A newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified. Conclusion: Our study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU's routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.

AB - Objective: To describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU). Methods: Setting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients. Results: A newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified. Conclusion: Our study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU's routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.

KW - Infection

KW - Neonatal intensive care unit

KW - Neonate

KW - Outbreak

KW - Screening

KW - Vancomycin-resistant Enterococcus faecium

UR - http://www.scopus.com/inward/record.url?scp=85086620604&partnerID=8YFLogxK

U2 - 10.1186/s13756-020-00755-0

DO - 10.1186/s13756-020-00755-0

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 32546210

AN - SCOPUS:85086620604

SN - 2047-2994

VL - 9

JO - Antimicrobial Resistance and Infection Control

JF - Antimicrobial Resistance and Infection Control

IS - 1

M1 - 87

ER -

A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this