A robotic venous leg ulcer system reveals the benefits of negative pressure wound therapy in effective fluid handling

Aleksei Orlov, Marino Ciliberti, Rosa Somma, Amit Gefen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We applied a market-leading, single-use negative pressure wound therapy device to a robotic venous leg ulcer system and compared its fluid handling performance with that of standard of care, superabsorbent and foam dressings and compression therapy. For each tested product, we determined a metrics of retained, residual, evaporated and (potential) leaked fluid shares, for three exudate flow regimes representing different possible clinically relevant scenarios. The single-use negative pressure wound therapy system under investigation emerged as the leading treatment option in the aspects of adequate fluid handling and consistent delivery of therapeutic-level wound-bed pressures. The superabsorbent dressing performed reasonably in fluid handling (resulting in some pooling but no leakage), however, it quickly caused excessive wound-bed pressures due to swelling, after less than a day of simulated use. The foam dressing exhibited the poorest fluid handling performance, that is, pooling in the wound-bed as well as occasional leakage, indicating potential inflammation and peri-wound skin maceration risks under real-world clinical use conditions. These laboratory findings highlight the importance of advanced robotic technology as contemporary means to simulate patient and wound behaviours and inform selection of wound care technologies and products, in ways that are impossible to achieve if relying solely on clinical trials and experience.

Original languageEnglish
Article numbere14426
JournalInternational Wound Journal
Volume21
Issue number2
DOIs
StatePublished - Feb 2024

Keywords

  • bioengineering laboratory testing
  • chronic wounds
  • compression therapy
  • exudate management
  • superabsorbent and foam dressings

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