A retrospective clinical analysis of 20 cases of congenital lung masses

Noa Gilad, Yael Furman, Alina Weissmann-Brenner

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Congenital-pulmonary-airway-malformation (CPAM) and bronchopulmonary-sequestration (BPS) are rare conditions. The objective of this study was to describe the sonographic characteristics and prenatal course of fetal lung mass. Methods: A retrospective study on 20 pregnancies with CPAM and BPS diagnosed during 2018–2018 was performed. Data evaluated included gestational age (GA) at diagnosis, size of lesion, CPAM-volume-ratio (CVR), associated sonographic findings and pregnancy outcome. Results: Fourteen cases of CPAM and six cases of BPS were evaluated. The average GA at diagnosis was 22 weeks’-gestation (range 17–26). 66% were macrocystic–multicystic. Five cases of BPS (71.4%) had other structural anomalies. None of the fetuses with CPAM had additional anomalies. Four pregnancies (20%) underwent termination due to severe hydrops fetalis. Two cases of CPAM (15%) had spontaneous resolution by 30 week’s-gestation; three cases (20%) continued to grow during pregnancy and all the rest reached their largest size at 25–28 week’s-gestation. Most cases delivered at term (average 37.6 range 32.2–41.4). Two children had lobectomy at 11 and 12 months of life. Conclusions: Careful follow-up during pregnancy may result in term delivery of adequate-for-gestational-age newborns, with no need for admission to the NICU, with only 10% need for lobectomy during the first year of life.

Original languageEnglish
JournalJournal of Maternal-Fetal and Neonatal Medicine
DOIs
StateAccepted/In press - 2020

Keywords

  • bronchopulmonary sequestration
  • Congenital pulmonary adenoid malformation
  • CPAM volume ratio
  • hydrops fetalis
  • mediastinal shift

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