A reappraisal of neonatal blood chemistry reference ranges using the NOVA M electrodes

S. Dollberg*, R. Bauer, R. Lubetzky, F. B. Mimouni

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The objective of this study is to establish new reference ranges for whole blood electrolytes, gases, and selected chemistries in normal healthy newborn infants obtained from cord blood and at 2-4 hours of life based on modern analytic techniques. Healthy appropriate-for-gestational age (AGA), term infants were studied. Whole venous cord blood and blood drawn at 2-4 hours of life were analyzed for gases, sodium, potassium, chloride, ionized calcium, ionized magnesium, hemoglobin, and hematocrit. Concentrations for blood glucose and blood urea nitrogen were close to older published concentrations. Na+, K+, and C1- were significantly different and had much narrower normal margins. New norms are included for blood gases, lactate, iCa, and iMg. We offer a range of values for often-measured blood chemistries in term, healthy infants, using modern laboratory methods. These values could serve as more up-to-date references compared with older values found in major textbooks of Neonatology.

Original languageEnglish
Pages (from-to)433-439
Number of pages7
JournalAmerican Journal of Perinatology
Issue number8
StatePublished - 2001
Externally publishedYes


  • Cord blood
  • Normal values
  • Venous blood


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